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Insulin Resistance: The Root of Metabolic Disease

Insulin resistance is the common thread linking type 2 diabetes, heart disease, PCOS, fatty liver, and obesity. Addressing it through diet is one of the most powerful health interventions available.

What Is Insulin Resistance?

Insulin is the hormone that tells your cells to absorb glucose from the blood. When you eat a high-carbohydrate diet over many years, your cells are constantly flooded with insulin. Eventually, they stop responding effectively — like neighbours who stop answering a door that never stops knocking.

The body responds by producing even more insulin, creating a vicious cycle. Blood insulin levels rise, fat storage increases (particularly around the abdomen), inflammation worsens, and metabolic dysfunction accelerates.

The critical insight is that insulin resistance often develops 10–15 years before blood sugar rises enough to be diagnosed as diabetes. This silent period is when the most damage occurs — and when dietary intervention is most effective.

Our team includes Steven Hamley, a PhD researcher at Deakin University studying the pathophysiology of insulin resistance, and Dr Helena Popovic, a medical doctor and author whose research explores the fructose–insulin resistance connection.

Conditions Linked to Insulin Resistance

Insulin resistance is not a single disease — it is the metabolic dysfunction underlying many chronic conditions.

  • Type 2 diabetes
  • Heart disease and atherosclerosis
  • Polycystic ovary syndrome (PCOS)
  • Non-alcoholic fatty liver disease (NAFLD)
  • Obesity and visceral fat accumulation
  • Alzheimer's disease (sometimes called 'type 3 diabetes')
  • Certain cancers
  • Chronic inflammation

Key Blood Markers We Track

Ask your GP for these tests. We help you interpret the results and track improvement over time.

Fasting Insulin

Optimal: < 8 mIU/LConcern: > 12 mIU/L

The earliest marker of insulin resistance — often elevated years before blood sugar rises.

Fasting Glucose

Optimal: 4.0–5.4 mmol/LConcern: > 5.5 mmol/L

Standard blood sugar test. By the time this is elevated, insulin resistance is already well established.

HbA1c

Optimal: < 5.7% (39 mmol/mol)Concern: > 5.7%

Average blood sugar over the last 2–3 months. The gold standard for tracking progress over time.

Triglyceride/HDL Ratio

Optimal: < 1.0Concern: > 1.7

A simple ratio from your standard lipid panel. A high ratio is a strong predictor of insulin resistance.

HOMA-IR

Optimal: < 1.0Concern: > 2.0

Calculated from fasting glucose and fasting insulin. The most widely used research measure of insulin resistance.

How We Help

1

Reduce Dietary Carbohydrate

Carbohydrates are broken down into glucose, which triggers insulin release. Reducing carbs lowers the insulin demand on your body, allowing cells to regain sensitivity.

2

Prioritise Whole Foods

Processed foods — especially those containing refined seed oils, sugar, and refined grains — drive inflammation and worsen insulin resistance. We focus on nutrient-dense whole foods.

3

Consider Time-Restricted Feeding

Giving your body extended periods without food allows insulin levels to drop and cells to recover. We may incorporate intermittent fasting protocols tailored to your lifestyle.

4

Track What Matters

We monitor fasting insulin, glucose, HbA1c, and lipid markers to measure real metabolic improvement — not just weight on a scale.

5

Address Root Causes

Poor sleep, chronic stress, and sedentary behaviour all worsen insulin resistance. We take a holistic view and address contributing lifestyle factors.

Don't Wait for a Diagnosis

Insulin resistance is reversible — especially when caught early. Book a free 15-minute consultation to discuss your blood work and find out how dietary changes can improve your metabolic health.